Blistering and scarring may occur in the eyes, mouth, esophagus, larynx, and on the vulva. Other names include cicatricial pemphigoid, oral pemphigoid and ocular pemphigoid. Treatment strategies in mucous membrane pemphigoid article pdf available in therapeutics and clinical risk management 43. Like other forms of pemphigoid, the disorder is characterized by the formation of autoantibodies against structural proteins of the dermalepidermal junction. Bullous pemphigoid bp this strain is limited to the skin. Mucous membrane pemphigoid is a rare, chronic, blistering and scarring disease that affects the oral and ocular mucosa. A clinical formocular cicatricial pemphigoid ocpmay result in blindness if it involves the eyes. Mucous membrane pemphigoid mmp is an autoimmune blistering disorder that is characterized by subepithelial blisters. Abstract lichen planus pemphigoides lpp is a rare autoimmune subepidermal blistering disease characterized by the coexistence of both lichen planus and bullous pemphigoid or mucous membrane pemph. Other mucosal sites that might be affected include the nasopharnyx, larynx, genitalia, rectum, and esophagus.
If it involves the deeper parts of the throat, it may cause respiratory compromise. Various basement membrane zone components have been identified as targets of autoantibodies in mmp and the disease is characterised by dermatologists based on these components. Mucous membrane pemphigoid mmp is a rare, chronic, autoimmune, subepithelial blistering and erosive disease that affects the mucosal surfaces of the mouth gi it seems to us that you have your javascript disabled on your browser. Outcomes for mucous membrane pemphigoid depend on early. Mucous membrane pemphigoid genetic and rare diseases.
Other moist surfaces of the body known as mucous membranes can. To be a member of this group you must have a form of pemphigoid or an associated illness or be a supporter. Levine early diagnosis and aggressive local and systemic therapy are critical to longterm visual outcome in cases of. Mucous membrane pemphigoid is a rare autoimmune blistering disease primarily affecting mucosal surfaces. Mucous membrane pemphigoid mmp this form of the disease affects the eyes, mouth, and throat. Scarring can result in severe structural changes to the vulva that may mimic the. Mucous membrane pemphigoid mmp is an autoimmune blistering disorder that is characterized by subepithelial bullae. Report of two cases of mucous membrane pemphigoid with. Mucous membrane pemphigoid is a heterogeneous subepithelial blistering disease that predominantly affects the mucous membranes, including the conjunctiva and occasionally the skin. Various basement membrane zone components have been identified as targets of.
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